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Merck
모든 사진(3)

주요 문서

I8000

Sigma-Aldrich

2-Iodosobenzoic acid

≥98% (TLC)

동의어(들):

IBA

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About This Item

Linear Formula:
OIC6H4CO2H
CAS Number:
Molecular Weight:
264.02
Beilstein:
1939973
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26

제품명

2-Iodosobenzoic acid,

분석

≥98% (TLC)

Quality Level

양식

powder

색상

white to off-white

mp

230 °C (dec.) (lit.)

저장 온도

−20°C

SMILES string

OC(=O)c1ccccc1[I]=O

InChI

1S/C7H5IO3/c9-7(10)5-3-1-2-4-6(5)8-11/h1-4H,(H,9,10)

InChI key

IFPHDUVGLXEIOQ-UHFFFAOYSA-N

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관련 카테고리

애플리케이션

For cleavage of tryptophanyl peptide bonds.

생화학적/생리학적 작용

2-Iodosobenzoic acid (IBA) may be used to study enzyme structure and activity. IBA is used as an oxidant which oxidizes vicinal sulfhydryls to disulfides (cysteine residues) within enzymes leading to their inactivation or conformational changes. IBA is also used to cleave tryptophanyl peptide bonds.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

J M Souza et al.
Archives of biochemistry and biophysics, 360(2), 187-194 (1998-12-16)
Rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was inactivated by peroxynitrite under biologically relevant conditions. The decrease of enzymatic activity followed an exponential function, and the concentration of peroxynitrite needed to inactivate 50% of 7 microM GAPDH (IC50) was 17 microM. Hydroxyl
T Kleinschmidt et al.
Biological chemistry Hoppe-Seyler, 370(8), 839-845 (1989-08-01)
The monomeric hemoglobin fractions of Chironomus thummi thummi (CTT) and Chironomus thummi piger (CTP) differ in the ratio of their components. The determination of the primary structure of the component CTP III was achieved by automatic Edman degradation of the
S Stoeva et al.
Biochemistry, 29(2), 527-534 (1990-01-16)
The amino acid sequence of the neutral zinc protease from Bacillus mesentericus strain 76 (MCP 76) has been determined by using peptides derived from digests with trypsin, chymotrypsin, and cyanogen bromide and from cleavage with o-iodosobenzoic acid. The peptides were
R J Duhé et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(1), 126-131 (1998-02-21)
The activation of Janus kinases (JAKs) is crucial for propagation of the proliferative response initiated by many cytokines. The proliferation of various cell lines, particularly those of hematopoietic origin, is also modulated by mediators of oxidative stress such as nitric
D Beale
The International journal of biochemistry, 21(5), 549-554 (1989-01-01)
1. Tryptic cleavage sites in bovine secretory component (SC) which become inaccessible when SC is bound to IgA dimer remained inaccessible at 60 degrees C and in 4 M urea at 37 degrees C. 2. This suggests the presence of

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