C9498

CL-82198

≥98% (HPLC), powder

• 동의어(들): N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide
• 실험식(Hill 표기법): C₁₇H₂₂N₂O₃
• CAS Number: 307002-71-7
• Molecular Weight: 302.37
• MDL number: MFCD12828877
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329775209
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to off-white
• solubility: DMSO: >10 mg/mL
• 주관자: Wyeth
• 저장 온도: 2-8°C
• SMILES string: O=C(NCCCCN1CCOCC1)c2cc3ccccc3o2
• InChI: 1S/C17H22N2O3/c20-17(16-13-14-5-1-2-6-15(14)22-16)18-7-3-4-8-19-9-11-21-12-10-19/h1-2,5-6,13H,3-4,7-12H2,(H,18,20)
• InChI key: KUJQEQAVMNFFAO-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder, binding within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom without zinc chelation.

CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder.

특징 및 장점

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable