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Merck
모든 사진(1)

주요 문서

B1125

Sigma-Aldrich

Bathocuproinedisulfonic acid disodium salt

7.2-9.1% purity dry basis (ICP), powder

동의어(들):

2,9-Dimethyl-4,7-diphenyl-1,10-phenantrolinedisulfonic acid disodium salt, Disodium bathocuproinedisulfonate

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About This Item

실험식(Hill 표기법):
C26H18N2Na2O6S2
CAS Number:
Molecular Weight:
564.54
MDL number:
UNSPSC 코드:
12171500
NACRES:
NA.47

제품명

Bathocuproinedisulfonic acid disodium salt, for spectrophotometric det. of Cu, Fe

분석

7.2-9.1% dry basis (ICP)

Quality Level

양식

powder

품질

for spectrophotometric det. of Cu, Fe

기술

titration: 90% using HCLO4 (Dry Basis)

색상

white to beige

solubility

H2O: 50 mg/mL

적합성

suitable for determination of copper

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

[Na+].[Na+].[S](=O)(=O)([O-])c1c(nc2c3nc(c(c(c3ccc2c1c5ccccc5)c4ccccc4)[S](=O)(=O)[O-])C)C

InChI

1S/C26H20N2O6S2.2Na/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2

InChI key

RNGKZLRAVYPLJC-UHFFFAOYSA-L

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일반 설명

Bathocuproinedisulfonic acid is a strong copper chelator. It is used for the determination of copper and iron in biological samples.

애플리케이션

  • Bathocuproinedisulfonic acid disodium salt has been used as a copper chelator for specific assay in Arabidopsis seedlings.
  • It has been used as an electron chain-associated free radical production inhibitor for superoxide dismutase assay in cells.
  • It has been added to the culture media of trypanosomes as a copper chelator for the stabilization of cysteine.

기타 정보

Mixture of isomers

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Minglin Lang et al.
Neurobiology of aging, 34(11), 2604-2612 (2013-07-06)
Disruption of copper homeostasis has been implicated in Alzheimer's disease (AD) during the last 2 decades; however, whether copper is a friend or a foe is controversial. Within a genetically tractable Drosophila AD model, we manipulated the expression of human
Jennifer Lowe et al.
The Journal of biological chemistry, 279(25), 25986-25994 (2004-04-14)
Ccc2p is homologous to the human Menkes and Wilson copper ATPases and is herein studied as a model for human copper transport. Most studies to date have sought to understand how mutations in the human Menkes or Wilson genes impair
Shinya Ogawa et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 909, 34-36 (2012-11-17)
HPLC eluent systems employing acetonitrile and methanol were evaluated for the quantitation of glutathione (GSH) and phytochelatin (PC(n)), a family of peptides implicated in heavy-metal detoxification in higher plants. The detection system is based on the dequenching of copper(I)-bathocuproine disulfonate
Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue.
Weydert CJ and Cullen JJ
Nature Protocols, 5, 51-66 (2010)
Shinya Ogawa et al.
Analytical chemistry, 81(21), 9199-9200 (2009-09-30)
Reoptimization of analytical conditions was performed for a high-performance liquid chromatographic (HPLC) detection system for Cu(I) chelators based on the dequenching of Cu(I)-bathocuproine disulfonate complexes that occurs in the presence of Cu(I) chelators. The revision corrects for emission and excitation

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