C9498

CL-82198

≥98% (HPLC), powder

• Synonyme(s) : N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide
• Formule empirique (notation de Hill) : C₁₇H₂₂N₂O₃
• Numéro CAS: 307002-71-7
• Poids moléculaire : 302.37
• Numéro MDL: MFCD12828877
• Code UNSPSC : 12352200
• ID de substance PubChem : 329775209
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to off-white
• Solubilité: DMSO: >10 mg/mL
• Auteur: Wyeth
• Température de stockage: 2-8°C
• Chaîne SMILES: O=C(NCCCCN1CCOCC1)c2cc3ccccc3o2
• InChI: 1S/C17H22N2O3/c20-17(16-13-14-5-1-2-6-15(14)22-16)18-7-3-4-8-19-9-11-21-12-10-19/h1-2,5-6,13H,3-4,7-12H2,(H,18,20)
• Clé InChI: KUJQEQAVMNFFAO-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder, binding within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom without zinc chelation.

CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder.

Caractéristiques et avantages

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable