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Key Documents

SAB3500465

Sigma-Aldrich

Monoclonal Anti-PUMA antibody produced in mouse

clone 2A9G5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Bbc3, Anti-Bcl-2 binding component 3, Anti-P53 upregulated modulator of apoptosis

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About This Item

MDL number:
MFCD04040564
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2A9G5, monoclonal

form

buffered aqueous solution

species reactivity

rat, mouse, human

technique(s)

indirect ELISA: suitable
western blot: suitable

NCBI accession no.

Q9BXH1

UniProt accession no.

Q9BXH1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BBC3(27113)

Related Categories

Immunogen

Mouse monoclonal PUMA antibody was raised against a recombinant protein corresponding to amino acids 76 – 170 of human PUMA-alpha.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
PM45250801
PM452508022D

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Ju Liu et al.
Cell death and differentiation, 21(11), 1792-1804 (2014-08-26)
Tumor suppressor p53 has a key role in maintaining genomic stability and preventing tumorigenesis through its regulation of cellular stress responses, including apoptosis, cell cycle arrest and senescence. To ensure its proper levels and functions in cells, p53 is tightly
Yun Zheng et al.
Cancer chemotherapy and pharmacology, 74(3), 487-495 (2014-07-18)
Exportin-1 (XPO1, CRM1) mediates the nuclear export of several key growth regulatory and tumor suppressor proteins. Cancer cells often overexpress XPO1 resulting in cytoplasmic mislocalization and aberrant activity of its target proteins. Orally bioavailable selective inhibitors of nuclear export (SINE)

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