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주요 문서

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1559006

USP

Prednisone

United States Pharmacopeia (USP) Reference Standard

동의어(들):

1,4-Pregnadiene-17α,21-diol-3,11,20-trione, 1-Cortisone, 17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione, Dehydrocortisone

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About This Item

실험식(Hill 표기법):
C21H26O5
CAS Number:
53-03-2
Molecular Weight:
358.43
Beilstein:
2065301
MDL number:
MFCD00003608
UNSPSC 코드:
41116107
PubChem Substance ID:
329750938
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

prednisone

제조업체/상표

USP

mp

236-238 °C (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1

InChI

1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

InChI key

XOFYZVNMUHMLCC-ZPOLXVRWSA-N

유전자 정보

human ... NR3C1(2908)

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관련 카테고리

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Prednisone USP reference standard for specified quality tests and assay use.

Also used to prepare standard, standard stock and internal standard solutions for the assay and performance tests according to the given below monographs of United States Pharmacopeia (USP):
  • Prednisone
  • Prednisone Tablets
  • Prednisone Oral Solution
  • Hydrocortisone Tablets

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

픽토그램

Health hazard
GHS08

신호어

Warning

유해 및 위험 성명서

H373

예방조치 성명서

P260 - P314 - P501

Hazard Classifications

STOT RE 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Prednisone Oral Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 30(1), 3671-3671 (2020)
Florentien D O de Steenwinkel et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(7), 1705-1711 (2014-03-01)
Active rheumatoid arthritis (RA) during pregnancy and the presence of rheumatoid factor (RF) or anti-citrullinated protein antibodies (ACPAs) are associated with lower birth weight of the child. Moreover, treatment of the mothers with prednisone may shorten the gestational age at
O Teuffel et al.
Leukemia, 25(8), 1232-1238 (2011-04-30)
This systematic review and meta-analysis compared the efficacy and toxicity of dexamethasone (DEX) versus prednisone (PRED) for induction therapy in childhood acute lymphoblastic leukemia (ALL). We searched biomedical literature databases and conference proceedings for randomized controlled trials comparing DEX and
Ronald de Wit
European journal of cancer (Oxford, England : 1990), 41(4), 502-507 (2005-03-02)
Until now, the use of systemic chemotherapy for advanced androgen-independent prostate cancer has had very little to offer to patients. However, in 2004, two large randomised trials investigating docetaxel vs. mitoxantrone have both demonstrated survival improvements, and, in one of
Karim Fizazi et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(7), 723-731 (2015-01-28)
Orteronel (TAK-700) is an investigational, nonsteroidal, reversible, selective 17,20-lyase inhibitor. This study examined orteronel in patients with metastatic castration-resistant prostate cancer that progressed after docetaxel therapy. In our study, 1,099 men were randomly assigned in a 2:1 schedule to receive
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