SML3822

SA-15-P

≥98% (HPLC)

• 동의어(들): N-[4-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethoxy]phenyl]-2-furancarboxamide
• 실험식(Hill 표기법): C₂₆H₂₄N₂O₄
• CAS Number: 852846-00-5
• Molecular Weight: 428.48
• UNSPSC 코드: 51111800
• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C

설명

생화학적/생리학적 작용

LAG-3 (CD223) inhibitor that blocks LAG-3 interactions with both major histocompatibility complex class II (MHCII) and fibrinogen-like protein 1 (FGL1).

SA-15-P is a LAG-3 (CD223) inhibitor that blocks LAG-3 interactions with both major histocompatibility complex class II and fibrinogen-like protein 1 by cell-free (MHCII IC50 = 4.21 μM & FGL1 IC50 = 6.52 μM) and cell-based binding assays (IC50 ~15 μM against 150 ng/mL or 1.5 nM FGL1-hFc binding to stable LAG-3-expressing CHO-K1 cell line).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable