SML3782

Omadacycline tosylate

≥97% (HPLC)

• 동의어(들): MK-2764 tosylate, (4S,4aS,5aR,12aS)-4,7-bis(Dimethylamino)-9-(2,2-dimethylpropylaminomethyl)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide, 4-methylbenzenesulfonate, Amadacycline tosylate, BAY 73-7388 tosylate, MK 2764 tosylate, MK2764 tosylate, PTK 0796 tosylate, PTK-0796 tosylate, PTK0796 tosylate
• 실험식(Hill 표기법): C₂₉H₄₀N₄O₇·C₇H₈O₃S
• CAS Number: 1075240-43-5
• Molecular Weight: 728.85
• MDL number: MFCD28167752
• UNSPSC 코드: 51111800
• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: yellow to orange
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: -10 to -25°C

설명

생화학적/생리학적 작용

Omadacycline (amadacycline, PTK 0796) is an orally active, potent tetracycline-class antibacterial against broad gram-positive and some gram-negative bacteria, including strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). Omadacycline is also active against Haemophilus influenzae (H. influenzae) and atypical and anaerobic pathogens, including Legionella pneumophila, Mycoplasma spp., Ureaplasma spp., Bacteroides spp., and Clostridioides difficile. Unlike tetracycline, Omadacycline is active in vitro in the presence of the ribosomal protection protein Tet(O), despite its ribosomal binding site is similar to that of tetracycline.

Orally active, potent tetracycline-class antibacterial against broad gram-positive and some gram-negative bacteria.

주의사항

Hygroscopic

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H361d,H362
• 예방조치 성명서: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Hazard Classifications: Lact. - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable