SML3655

LockdownPro

≥97% (HPLC)

• 동의어(들): Tetraethyl 4,4′-((propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalate
• 실험식(Hill 표기법): C₃₉H₄₀O₁₀
• Molecular Weight: 668.73
• UNSPSC 코드: 12352200
• NACRES: NA.25

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: (oil or liquid)
• 색상: colorless to yellow
• 저장 온도: 2-8°C
• SMILES string: CC(C1=CC=C(C=C1)OC2=CC(C(OCC)=O)=C(C(OCC)=O)C=C2)(C3=CC=C(OC4=CC(C(OCC)=O)=C(C(OCC)=O)C=C4)C=C3)C
• InChI: 1S/C39H40O10/c1-7-44-35(40)31-21-19-29(23-33(31)37(42)46-9-3)48-27-15-11-25(12-16-27)39(5,6)26-13-17-28(18-14-26)49-30-20-22-32(36(41)45-8-2)34(24-30)38(43)47-10-4/h11-24H,7-10H2,1-6H3
• InChI key: ROEOSYBNNXMANC-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F that inhibits tissue invasion by PPM1F-overexpressing human cancer cells

LockdownPro, an esterified lockdown analog with better cell permeability, is a cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F. LockdownPro potently inhibits tissue invasion by PPM1F-overexpressing human cancer cells. It does not inhibit PPM1F in vitro.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable