SML3599

IMP-1575

≥98% (HPLC)

• 동의어(들): (+)-(R)-IMP-1575, (+)-IMP-1575, (R)-(+)-2-(Isobutylamino)-1-(4-(6-methylpyridin-2-yl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethan-1-one, (R)-1-[6,7-Dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylpropyl)amino]ethenone, (R)-IMP-1575
• 실험식(Hill 표기법): C₁₉H₂₅N₃OS
• Molecular Weight: 343.49
• UNSPSC 코드: 51111800
• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: oil
• 색상: , Faint yellow to yellow orange
• 저장 온도: 2-8°C
• SMILES string: CC1=CC=CC([C@@H]2N(CCC3=C2C=CS3)C(CNCC(C)C)=O)=N1
• InChI key: OVUGAMKQXDOHDJ-LJQANCHMSA-N

설명

생화학적/생리학적 작용

Donor substrate Pal-CoA-competitive hedgehog acyltransferase (HHAT) inhibitor with significantly higher potency than its structure analog RUSKI-201.

IMP-1575 is a donor substrate Pal-CoA-competitive (Ki = 38 nM) hedgehog acyltransferase (HHAT) inhibitor with significantly higher potency than its structure analog RUSKI-201 (IC50 = 0.75 vs. 2.0 μM, respectively, by Acyl-cLIP assay).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable