SML3503

EN523

≥98% (HPLC)

• 동의어(들): 1-(5-Methyl-2-furanyl)-4-(1-oxo-2-propen-1-yl)-2-piperazinone
• 실험식(Hill 표기법): C₁₂H₁₄N₂O₃
• CAS Number: 2094893-05-5
• Molecular Weight: 234.25
• MDL number: MFCD32859220
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: O=C1N(CCN(C1)C(C=C)=O)C2=CC=C(O2)C
• InChI: 1S/C12H14N2O3/c1-3-10(15)13-6-7-14(11(16)8-13)12-5-4-9(2)17-12/h3-5H,1,6-8H2,2H3
• InChI key: KYXPDOMFYBFXKO-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1

EN523 is a cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1. EN523 does not inhibit OTUB1 deubiquitination activity and serves as OTUB1 recruiter.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable