SML3191

Cotrimoxazole

≥98% (HPLC)

• 동의어(들): 4-Amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide mixt. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine, TMP/SMX, Trimethoprim/sulfamethoxazole
• 실험식(Hill 표기법): C₁₄H₁₈N₄O₃·5C₁₀H₁₁N₃O₃S
• CAS Number: 8064-90-2
• Molecular Weight: 1556.71
• UNSPSC 코드: 12352107
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: [S](=O)(=O)(Nc4n[o]c(c4)C)c3ccc(cc3)N.Nc1nc(c(cn1)Cc2cc(c(c(c2)OC)OC)OC)N
• InChI: 1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)
• InChI key: WZRJTRPJURQBRM-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Cotrimoxazole is a combination antibiotic consisting of one part trimethoprim to five parts sulfamethoxazole that is used to treat a variety of bacterial infections both Gram-positive and Gram-negative. Sulfamethoxazole inhibits bacterial dihydropteroate synthase while trimethoprim inhibits bacterial dihydrofolate reductase, thereby blocking the synthesis of nucleic acids.

combination antibiotic consisting of one part trimethoprim to five parts sulfamethoxazole

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H361d
• 예방조치 성명서: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable