SML1065

TR100

≥98% (HPLC)

• 동의어(들): 2-Cyano-3-[1-[3-(dimethylamino)propyl]-2-methyl-1H-indol-3-yl]-N-octyl-2-propenamide
• 실험식(Hill 표기법): C₂₆H₃₈N₄O
• CAS Number: 1128165-86-5
• Molecular Weight: 422.61
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825645
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: CC1=C(/C=C(C#N)\C(NCCCCCCCC)=O)C2=C(N1CCCN(C)C)C=CC=C2
• InChI: 1S/C26H38N4O/c1-5-6-7-8-9-12-16-28-26(31)22(20-27)19-24-21(2)30(18-13-17-29(3)4)25-15-11-10-14-23(24)25/h10-11,14-15,19H,5-9,12-13,16-18H2,1-4H3,(H,28,31)/b22-19-
• InChI key: XXRLIGWROLDOLS-QOCHGBHMSA-N

설명

생화학적/생리학적 작용

TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells.

TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells. TR100 selectively disrupts Tm5NM1/2 containing actin filaments. TR100 induces apoptosis in a panel of neural crest-derived tumor cell lines with no adverse effects on cardiac structure and function.

안전성 정보

• 유해 및 위험 성명서: H413
• 예방조치 성명서: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable