SML0608

A-412997 dihydrochloride

≥98% (HPLC)

• 동의어(들): N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide dihydrochloride
• 실험식(Hill 표기법): C₁₉H₂₃N₃O · 2HCl
• CAS Number: 1347744-96-0
• Molecular Weight: 382.33
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: Cl.Cl.N2(CCC(CC2)c3ncccc3)CC(=O)Nc1cc(ccc1)C
• InChI: 1S/C19H23N3O.2ClH/c1-15-5-4-6-17(13-15)21-19(23)14-22-11-8-16(9-12-22)18-7-2-3-10-20-18;;/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,21,23);2*1H
• InChI key: KIGNSSHMCNBHQX-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

A-412997 is a selective D4 agonist with Ki values of 12 and 7.9 nM for the rat and human receptors, and no affinity for other dopamine receptors at concentrations up to 1 mM. A-412997 improves short term memory and cognitive properties in rodent models.

A-412997 is a selective D4 agonist.

특징 및 장점

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable