SML0473

Noladin ether

≥98% (HPLC)

• 동의어(들): 2-Arachidonylglyceryl ether, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yloxy]-1,3-propanediol; 2-AG ether, HU 310
• 실험식(Hill 표기법): C₂₃H₄₀O₃
• CAS Number: 222723-55-9
• Molecular Weight: 364.56
• EC Number: 200-578-6
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solution
• 약물 제어: regulated under CDSA - not available from Sigma-Aldrich Canada
• 농도: 10 mg/mL in ethanol (1% w/v)
• 색상: colorless to light yellow
• 배송 상태: dry ice
• 저장 온도: −70°C
• SMILES string: O(C(CO)CO)CCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC
• InChI: 1S/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15-
• InChI key: CUJUUWXZAQHCNC-DOFZRALJSA-N

설명

생화학적/생리학적 작용

Noladin ether (2-Arachidonyl glycerol ether) is a CB1 agonist.

Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye.

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H319
• 예방조치 성명서: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 57.2 °F - closed cup
• Flash Point (°C): 14.0 °C - closed cup