SAB6010005

Anti-phospho-MAPT (S404) antibody, clone 11H10, Rabbit Monoclonal

recombinant, expressed in HEK293F cells

• 동의어(들): Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau), MAPT, MAPTL MTBT1 TAU
• UNSPSC 코드: 12352203

속성

• 재조합: expressed in HEK 293 F cells
• Quality Level: 100
• 결합: unconjugated
• 항체 생산 유형: primary antibodies
• 클론: 11H10, recombinant monoclonal
• 양식: liquid
• 분자량: 150 kDa
• 정제법: affinity chromatography
• 종 반응성: human
• 농도: 0.4mg/ml
• 기술: ELISA: 2000:10000; flow cytometry: 1:50-1:200; immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200
• 동형: IgG
• UniProt 수납 번호: P10636
• 배송 상태: wet ice
• 저장 온도: -10 to -25°C
• 타겟 번역 후 변형: phosphorylation (pSer404)

설명

일반 설명

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

면역원

A synthesized peptide derived from Human MAPT

서열

ST-pS-PS

물리적 형태

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

저장 및 안정성

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable