SAB4200370

Anti-PVRL4 antibody, Mouse monoclonal

clone N4.101.10, purified from hybridoma cell culture

• 동의어(들): Monoclonal Anti-Nectin-4/PVRL4 antibody produced in mouse, Monoclonal Anti-PVRL4 antibody produced in mouse, Anti-EDSS1, Anti-LNIR, Anti-Nectin-4, Anti-PRR4, Anti-PVRL4, Anti-Poliovirus receptor-related 4
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: N4.101.10, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 농도: ~1.0 mg/mL
• 기술: flow cytometry: 5-10 μg/test using using 1x10⁶ MDA-MB-231 cells; immunocytochemistry: 2.5-5 μg/mL using using MDA-MB-231 cells
• 동형: IgG1
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PVRL4(81607)

설명

일반 설명

Monoclonal Anti-Nectin-4/PVRL4 (mouse IgG1 isotype) is derived from the hybridoma R2.525.2 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human nectin4-Fc recombinant protein. Nectin-4 belongs to the family of Nectins. It forms homo-cis-dimers and then homo- or hetero-trans-dimers through the extracellular region in a Ca²⁺-independent manner. Nectin-4 is expressed in placenta, ductal breast carcinoma and lung adenocarcinomas. It is one of the plasma membrane components of adherens junctions.

면역원

human Nectin4/Fc recombinant protein

애플리케이션

Monoclonal Anti-PVRL4 antibody produced in mouse has been used in immunocytochemistry and flow cytometry.

생화학적/생리학적 작용

Nectin-4 is involved in cell adhesion through trans homophilic and heterophilic interactions. Mutations in this gene are associated with ectodermal dysplasia-syndactyly syndrome type 1.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable