SAB4200230

Anti-DPP4/CD26 antibody, Mouse monoclonal

clone A6H, purified from hybridoma cell culture

• 동의어(들): Monoclonal Anti-ADABP, Monoclonal Anti-ADCP2, Monoclonal Anti-DPPIV, Monoclonal Anti-TP103, Monoclonal Anti-dipeptidyl-peptidase 4
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: unconjugated
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: A6H, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 농도: ~4.0 mg/mL
• 기술: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; indirect immunofluorescence: 20-40 μg/mL using methanol/acetone fixed HT-29 cells
• 동형: IgG1
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... DPP4(1803)

설명

일반 설명

Monoclonal Anti-DPP4/CD26 (mouse IgG1 isotype) is derived from the hybridoma A6H produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human fetal homogenates. Dipeptidyl peptidase-4 (DPP4) belongs to the S9B protein family, which cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides and peptide hormones. It is a type II transmembrane glycoprotein, expressed on the surface of many cell types.

면역원

human fetal homogenates.

애플리케이션

Monoclonal Anti-DPP4/CD26 antibody produced in mouse has been used in:

• enzyme linked immuno sorbent assay (ELISA)
• immunocytochemistry
• immunohistochemistry
• flow cytometry

생화학적/생리학적 작용

Dipeptidyl peptidase-4 (DPP4) is involved in the regulation of the biological activity of hormones and chemokines, such as glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. DPP4 inhibition maybe used to treat type 2 diabetes mellitus. It acts as a T cell activation molecule and regulates immunity and immune-mediated disorders.

물리적 형태

Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable