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Merck
모든 사진(3)

주요 문서

R7882

Sigma-Aldrich

Retinyl acetate

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

동의어(들):

Retinol acetate, Vitamin A acetate

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About This Item

실험식(Hill 표기법):
C22H32O2
CAS Number:
Molecular Weight:
328.49
Beilstein:
1915439
EC Number:
MDL number:
UNSPSC 코드:
12352205
eCl@ss:
34058009
PubChem Substance ID:
NACRES:
NA.75

생물학적 소스

synthetic

제품 라인

BioReagent

분석

≥90% (HPLC)

양식

solid or viscous liquid

효능

~2,800,000 I.U. per g

분자량

Mw 328.49 g/mol

기술

cell culture | mammalian: suitable

색상

light yellow to dark yellow

mp

57-58 °C

solubility

absolute ethanol: 25 mg/mL (lit.)

저장 온도

−20°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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일반 설명

Retinyl-acetate is a natural and ester derivative of vitamin A. It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

애플리케이션

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC) and as a supplement in the preparation of the complete medium.

생화학적/생리학적 작용

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.

기타 정보

All trans

제조 메모

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

개인 보호 장비

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Hormones and Vitamins in Cancer Treatment, 247-247 (1990)
Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level
Ortega F, et al.
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Cancer chemoprevention uses natural, synthetic, or biological substances to reverse, suppress, or prevent either the initial phase of carcinogenesis or the progression of neoplastic cells to cancer. It holds promise for overcoming problems associated with the treatment of late-stage cancers.
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Pediatric research, 67(6), 619-623 (2010-03-11)
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문서

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apoptosis, and embryonic development.

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