R1033

RN-1747

≥98% (HPLC)

• 동의어(들): 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine;, 1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-piperazine
• 실험식(Hill 표기법): C₁₇H₁₈ClN₃O₄S
• CAS Number: 1024448-59-6
• Molecular Weight: 395.86
• MDL number: MFCD04154169
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329823995
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: light yellow to light tan
• solubility: DMSO: ≥10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: [O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)N2CCN(CC2)Cc3ccccc3
• InChI: 1S/C17H18ClN3O4S/c18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2
• InChI key: ZNLVYSJQUMALEO-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs.

TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs. TRPV4 is a nociceptor playing an important role in inflammatory and neuropathic mechanical hyperalgesia in rodent models apparently specifically activated under pathological conditions.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable