P5117

Anti-Peripherin antibody, Mouse monoclonal

clone 8G2, purified from hybridoma cell culture

• 동의어(들): Anti-NEF4, Anti-PRPH1
• MDL number: MFCD01633973
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: 8G2, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: rat, bovine, pig, mouse, rabbit, feline, human
• 기술: immunohistochemistry: suitable; indirect ELISA: suitable; microarray: suitable; western blot: 0.5-1.0 μg/mL using total cell extract from rat PC12 cells
• 동형: IgG1
• UniProt 수납 번호: P41219
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PRPH(5630) ; mouse ... Prph(19132) ; rat ... Prph(24688)

설명

일반 설명

Monoclonal Anti-Peripherin (mouse IgG1 isotype) is derived from the 8G2 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with the full-length recombinant rat peripherin. Peripherin was originally identified as a neuronal intermediate filament protein-(IF) is thought to be expressed only in the peripheral nervous system (PNS).

Peripherin is an intermediate filament protein. It is expressed in peripheral and enteric neurons. The gene encoding this protein is localized on rat chromosome 7.

면역원

full-length recombinant rat peripherin.

애플리케이션

Anti-Peripherin antibody, Mouse monoclonal has been used in:

• immunohistochemistry
• western blotting
• enzyme linked immunosorbent assay (ELISA)
• immunofluorescence staining

생화학적/생리학적 작용

Peripherin is upregulated during pheochromocytoma PC12 cell differentiation. Later studies have detected peripherin also in certain central nervous system (CNS) neurons.

eripherin has been linked with axonal extension and regeneration of nerve fibers. It also has a role in neurite outgrowth propagation. Peripherin is a substrate of protein kinase B/Akt. Phosphorylation of this protein is induced after nerve injury.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable