C4881

Chlortetracycline hydrochloride

≥91.0% dry basis (HPLC)

• 동의어(들): 7-Chlorotetracycline hydrochloride
• 실험식(Hill 표기법): C₂₂H₂₃ClN₂O₈ · HCl
• CAS Number: 64-72-2
• Molecular Weight: 515.34
• Beilstein: 3858364
• EC Number: 200-591-7
• MDL number: MFCD00082440
• UNSPSC 코드: 51102829
• PubChem Substance ID: 24892735
• NACRES: NA.85

속성

• Quality Level: 200
• 분석: ≥91.0% dry basis (HPLC)
• 양식: powder
• pKa(25 °C): 3.3; 7.4; 9.3
• mp: 210-215 °C (dec.) (lit.)
• solubility: 1 M NaOH: 50 mg/mL
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: protein synthesis | interferes
• 저장 온도: −20°C
• SMILES string: Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O
• InChI: 1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
• InChI key: CBHYYLPALVVVEY-LYNLVHCPSA-N

설명

일반 설명

Chemical structure: tetracycline

애플리케이션

Chlortetracycline was used in fluorescence assays to detect the Ca+2 influx required for the completion of acrosome reaction in human spermatozoa.

생화학적/생리학적 작용

Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens. It inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. It is effective against Gram-positive and to a lesser degree Gram-negative bacteria than tetracycline.
Mode of Resistance: Loss of cell wall permeability.

기타 정보

If stored frozen, chlortetracycline hydrochloride is expected to remain stable at least four years.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H317,H319,H335,H361fd
• 예방조치 성명서: P202 - P261 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves