B5438

Balsalazide disodium salt hydrate

• 동의어(들): 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
• 실험식(Hill 표기법): C₁₇H₁₃N₃Na₂O₆ · xH₂O
• CAS Number: 213594-60-6
• Molecular Weight: 401.28 (anhydrous basis)
• MDL number: MFCD18632541
• UNSPSC 코드: 12352100
• PubChem Substance ID: 329773261
• NACRES: NA.25

속성

• 분석: ≥99% (HPLC)
• 양식: powder
• 저장 온도: 2-8°C
• SMILES string: O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
• InChI: 1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
• InChI key: ZZZXQZHSFPVNCR-HVARVCSCSA-L

설명

생화학적/생리학적 작용

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable