AV31121

Anti-RBPJ antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-CBF1, Anti-IGKJRB, Anti-IGKJRB1, Anti-KBF2, Anti-MGC61669, Anti-RBP-J, Anti-RBPJK, Anti-Recombination signal binding protein for immunoglobulin kappa J region
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: 56 kDa
• 종 반응성: dog, bovine, guinea pig, rabbit, rat, human, horse
• 농도: 0.5 mg - 1 mg/mL
• 기술: immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• NCBI 수납 번호: NP_005340
• UniProt 수납 번호: Q06330
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... RBPJ(3516)

설명

일반 설명

RBPJ is a transcriptional repressor that targets notch signaling. Studies have reported that it can activate the K14/vGPCR promoter of Kaposi′s sarcoma-associated herpesvirus (KSHV). Furthermore, RBPJ has also been implicated in the differentiation suppression of myogenic precursor cells.
Rabbit Anti-RBPJ antibody recognizes human, bovine, canine, and mouse RBPJ.

면역원

Synthetic peptide directed towards the C terminal region of human RBPSUH

애플리케이션

Rabbit Anti-RBPJ antibody can be used for western blot (0.25μg/ml) assays.

생화학적/생리학적 작용

RBPSUH is a DNA binding protein that activates a full transcriptional response but only demonstrates partial anti-apoptotic activity. RTA-mediated redirection of RBPSUH activity from repression to activation is critical for lytic viral replication.

서열

Synthetic peptide located within the following region: RPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS

물리적 형태

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable