추천 제품
생물학적 소스
goat
Quality Level
결합
agarose conjugate
항체 형태
affinity isolated antibody
항체 생산 유형
secondary antibodies
클론
polyclonal
양식
PBS suspension
종 반응성
human
반응하면 안 됨
rat, mouse
용량
3-4 mg/mL binding capacity (human IgA)
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
일반 설명
Binding Capacity: One mL of antibody binds 3-4 mg human IgA. Elution Capacity is 2-4 mg/mL.
IgA antibody plays an essential role in mucosal immunity. It has shown to bind immunogens/pathogens to restrict them from entering the mucosal membrane. The Anti-Human IgA (α-chain specific) product increases sensitivity to human IgA without cross-reactivity to other substances. Offering minimal interspecies cross reactivity to mouse or a rat, making it ideal for use in screening antibodies produced by a hybridoma cells containing a mouse or a rat immunoglobulins.
면역원
IgA produced from transformed cell line of human Epstein-Barr virus.
애플리케이션
Affinity chromatography using anti-human IgA antibody linked to agarose was performed to purify proteins from 2E9IgA1 transfectant cells.
Anti-Human IgA (α-chain specific)-Agarose antibody produced in goat has been used in affinity chromatography and quantitative enzyme linked immunosorbent assay (ELISA).
물리적 형태
Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Susanne Wolbank et al.
Journal of virology, 77(7), 4095-4103 (2003-03-14)
We have previously generated human monoclonal anti-human immunodeficiency virus type 1 (anti-HIV-1) antibodies 2F5IgG and 2G12IgG with an exceptional cross-clade neutralizing potential. 2F5IgG and 2G12IgG passively administrated to macaques were able to confer complete protection from both intravenous and mucosal
Poor ex vivo induction of T-cell responses to idiotype or tumor cell lysate-pulsed autologous dendritic cells in advanced pre-treated multiple myeloma
Garderet L, et al.
Leukemia & Lymphoma, 47(7), 1340-1347 (2006)
Suckow MA, et al.
The Laboratory Rat (2005)
Y J Wen et al.
Blood, 97(6), 1750-1755 (2001-03-10)
Multiple myeloma (MM) is a B-cell malignancy. The monoclonal immunoglobulin, secreted by myeloma plasma cells, carries unique antigenic determinants (idiotype [Id]) that can be regarded as a tumor-specific antigen. Id-based immunotherapy has been explored in myeloma patients for the purpose
J Berdoz et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(6), 3029-3034 (1999-03-17)
The hallmark of a mucosal immune response is the production of antigen-specific secretory IgA (S-IgA) antibodies in external secretions. S-IgA consists of ten polypeptides produced in two different cell lineages. The heavy and light chains in plasma cells assemble into
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