A9511

Albumin from human serum

lyophilized powder, ≥97% (agarose gel electrophoresis)

• 동의어(들): HSA
• CAS Number: 70024-90-7
• EC Number: 274-272-6
• MDL number: MFCD00081418
• UNSPSC 코드: 12352202
• eCl@ss: 42010201
• NACRES: NA.25

속성

• 생물학적 소스: human
• 분석: ≥97% (agarose gel electrophoresis)
• 양식: lyophilized powder
• 분자량: monomer calculated mol wt 66478 Da
• 기술: ELISA: suitable; tissue culture: suitable; western blot: suitable
• 불순물: HIV I and HIVII, HCV and HBsAg, tested negative
• solubility: H₂O: soluble 50 mg/mL
• UniProt 수납 번호: P02768
• 저장 온도: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N
• 유전자 정보: human ... ALB(213)

설명

일반 설명

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Human albumin possess a molecular weight of 67 kDa.

애플리케이션

Albumin from human serum has been used:

• to standardize the column for molecular-exclusion chromatography
• to prepare the tobacco mosaic virus (TMV)-poly ethylene glycol (PEG8)-serum albumin (SA) particles
• to analyze its modifications after oxidation using a Fenton system

Albumin-bound fluorescence was used in serum of patients with chronic renal failure.

생화학적/생리학적 작용

Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator in liver disease. Oxidative modification of albumin is seen in advanced liver disease.

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

제조 메모

Prepared using method IV of Cohn, E.J., et al., J. Am. Chem. Soc., 69, 1753 (1947).

기타 정보

View more information on human serum albumin.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves