74667

Nourseothricin sulfate

≥85% (HPLC)

• CAS Number: 96736-11-7
• MDL number: MFCD00165013
• UNSPSC 코드: 51102829
• NACRES: NA.85

속성

• 생물학적 소스: Streptomyces noursei
• Quality Level: 100
• 분석: ≥85% (HPLC)
• 양식: solid
• 색상: white to light brown
• solubility: H₂O: soluble 200 mg/mL
• 적합성: suitable for (selection agent for molecular genetic research work)
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria; fungi; mycobacteria; mycoplasma; parasites; viruses; yeast
• 동작 모드: protein synthesis | interferes
• 저장 온도: 2-8°C
• SMILES string: [S](=O)(=O)(O)O.N4[C@H]5[C@H](N=C4N[C@@H]6O[C@@H]([C@@H]([C@H]([C@H]6NC(=O)C[C@@H](N)CCCNC(=O)C[C@@H](N)CCCNC(=O)C[C@@H](N)CCCN)O)OC(=O)N)CO)C(=O)NC[C@H]5O.N1[C@H]2[C@H](N=C1N[C@@H]3O[C@@H]([C@@H]([C@H]([C@H]3NC(=O)C[C@@H](N)CCCN)O)OC(=O)N)CO)C(=O)NC[C@H]
• InChI key: HEPYPTBGGNPPAP-SPCBHCMPSA-N

설명

일반 설명

Chemical structure: peptidyl nucleoside

애플리케이션

Noursethricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.

생화학적/생리학적 작용

Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.

Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.

포장

10mg, 100mg

기타 정보

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves