P3700000
Propylthiouracil
European Pharmacopoeia (EP) Reference Standard
동의어(들):
6-Propyl-2-thiouracil, 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone, 4-Hydroxy-2-mercapto-6-propylpyrimidine
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C7H10N2OS
CAS Number:
Molecular Weight:
170.23
Beilstein:
130039
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
pharmaceutical primary standard
설명
enzyme inhibitor
API family
propylthiouracil
제조업체/상표
EDQM
mp
218-220 °C (lit.)
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-8°C
SMILES string
CCCC1=CC(=O)NC(=S)N1
InChI
1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI key
KNAHARQHSZJURB-UHFFFAOYSA-N
유전자 정보
human ... DIO1(1733) , TPO(7173)
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일반 설명
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
애플리케이션
Propylthiouracil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
포장
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
기타 정보
Sales restrictions may apply.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Eleni Memi et al.
Journal of pediatric endocrinology & metabolism : JPEM, 25(3-4), 331-343 (2012-07-10)
Antithyroid drugs (ATDs) have been widely and effectively used for the treatment of pediatric and adult thyrotoxicosis for more than a half century. Since the very beginning of ATD use, reports of hepatic dysfunction related to propylthiouracil (PTU) therapy have
Spiros Karras et al.
Journal of pediatric endocrinology & metabolism : JPEM, 25(7-8), 623-630 (2012-11-20)
Propylthiouracil (PTU), carbimazole (CMZ) and methimazole (MMI) are the most common drugs used today in cases of adolescent thyrotoxicosis. Skepticism has been growing regarding the use of PTU in childhood and its association with severe liver failure. The aim of
Daniel Glinoer et al.
Current opinion in endocrinology, diabetes, and obesity, 19(5), 402-407 (2012-07-24)
To bring to the attention of healthcare professionals the additional information on propylthiouracil (PTU)-related hepatotoxicity, based on a reanalysis of medical files reported to the Food and Drug Administration (1982-2008) for acute liver failure in PTU-treated hyperthyroid patients, and propose
Long-term propylthiouracil use and acute myeloid leukemia: a case report and review of the literature.
Daniele Focosi et al.
Annals of hematology, 87(3), 233-235 (2007-09-12)
A Rambaldi et al.
Liver, 21(6), 398-404 (2002-03-21)
The aim of this review was to determine the benefits and adverse effects of propylthiouracil for patients with alcoholic liver disease. Systematic Cochrane Review of randomised clinical trials. The Cochrane Hepato-Biliary Controlled Clinical Trials Register, The Cochrane Library, MEDLINE, and
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