M8506
Methimazole
analytical standard
동의어(들):
1-Methyl-2-mercaptoimidazole, MET, 1-Methyl-2-imidazolethiol, 2-Mercapto-1-methylimidazole
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C4H6N2S
CAS Number:
Molecular Weight:
114.17
Beilstein:
108646
EC Number:
MDL number:
UNSPSC 코드:
41116107
eCl@ss:
39161002
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
analytical standard
Quality Level
분석
≥99%
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
144-147 °C (lit.)
응용 분야
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
형식
neat
SMILES string
CN1C=CNC1=S
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
유전자 정보
human ... TPO(7173)
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일반 설명
Methimazole belongs to the chemical class of thioureylene compounds, used as an anti-thyroid drug in the management of hyperthyroidism.
애플리케이션
Beclomethasone dipropionate analytical standard can be used as follows:
- Silver/graphene-modified carbon-paste electrode (AgGCPE) based electrochemical determination of methimazole
- Development of a surface-enhanced Raman scattering (SERS) based method to estimate propylthiouracil and methimazole using sodium alginate-protected silver nanoparticles as SERS substrate
- Detection of methimazole at ultra-trace limits using surface-enhanced Raman spectroscopy based on gold nanoparticles (AuNPs) substrate
- Quantitative analysis of human blood samples for methimazole using high-performance liquid chromatography-tandem mass spectrometric (HPLC-MS/MS) method
- Electrochemical determination of methimazole in pharmaceutical tablet and human blood serum samples by molecularly imprinted polymer (MIP)- pencil graphite electrode (PGE) based sensor
기타 정보
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
이미 열람한 고객
Determination of methimazole in urine with the iodine-azide detection system following its separation by reversed-phase high-performance liquid chromatography
Zakrzewski R
Journal of Chromatography. B, Biomedical Applications, 869(1-2), 67-74 (2008)
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
Francesco Isaia et al.
Journal of medicinal chemistry, 51(13), 4050-4053 (2008-06-06)
The antithyroid drug methimazole (MMI) reacts with molecular iodine to form, in a multistep process, 1-methylimidazole as final product. In this process, the charge transfer complex MMI-I 2 and the ionic disulfide [(C 4H 6N 2S-) 2] (2+) ( 1
Coralie Leblicq et al.
Pediatrics, 131(2), e616-e619 (2013-01-09)
A 15-year-old girl presented with chorea as a first sign of Graves' hyperthyroidism. Chorea abated with antithyroid drug treatment and reappeared when hyperthyroidism recurred but not when thyrotropin receptor antibodies increased after administration of (131)I. Therefore, chorea in this patient
F S Boretti et al.
Journal of veterinary internal medicine, 27(2), 377-381 (2013-02-13)
Transdermal methimazole is an acceptable alternative to oral treatment for hyperthyroid cats. There are, however, no studies evaluating the duration of T4 suppression after transdermal methimazole application. Such information would be valuable for therapeutic monitoring. To assess variation in serum
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