45706

Warfarin

PESTANAL^®, analytical standard

• 동의어(들): 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin, Coumafene
• 실험식(Hill 표기법): C₁₉H₁₆O₄
• CAS Number: 81-81-2
• Molecular Weight: 308.33
• Beilstein: 8868198
• EC Number: 201-377-6
• MDL number: MFCD00006854
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329756915
• NACRES: NA.24

속성

• Grade: analytical standard
• Quality Level: 100
• 제품 라인: PESTANAL^®
• 유통기한: limited shelf life, expiry date on the label
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• mp: 162-164 °C (lit.)
• 응용 분야: agriculture; environmental
• 형식: neat
• SMILES string: CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
• InChI: 1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
• InChI key: PJVWKTKQMONHTI-UHFFFAOYSA-N
• 유전자 정보: human ... VKORC1(79001)

설명

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food.

생화학적/생리학적 작용

Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z.

주의사항

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

법적 정보

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06,GHS08,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330,H360D,H372,H411
• 예방조치 성명서: P202 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1 Oral
• 표적 기관: Blood
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3