FCMAB108A4

Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 Alexa Fluor^™ 488

clone 5D11G5, from mouse, ALEXA FLUOR^™ 488

• 동의어(들): CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, OTTHUMP00000061876, SB1.8, SMC1, SMC1A, SMC1L1, SMC1alpha, SMCB, Sb1.8, Smcb
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: ALEXA FLUOR^™ 488
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 5D11G5, monoclonal
• 종 반응성: human, Xenopus, bovine
• 기술: flow cytometry: suitable; western blot: suitable
• 동형: IgG1
• NCBI 수납 번호: NM_006306
• UniProt 수납 번호: Q14683
• 배송 상태: wet ice
• 타겟 번역 후 변형: phosphorylation (pSer957)
• 유전자 정보: human ... SMC1A(8243)

설명

일반 설명

SMC (structural maintenance of chromosomes) proteins are Involved in chromosome cohesion during cell cycle and in DNA repair. ATM phosphorylates SMC1 on Ser957 and Ser966 both in vitro and in vivo. Phosphorylated SMC1 is part of the complex that functions as a downstream effector in both the ATM/NBS1 branch and the ATR/MSH2 branch of S-phase checkpoint.

특이성

Antibody recognizes SMC1 phosphorylolated at Ser957.

Predicted to cross-react with xenopus and bovine based on sequence homology

면역원

Epitope: Phosphorylated at and around Ser957

KLH-conjugated, synthetic peptide corresponding to human SMC1 phosphorylated at Ser957

애플리케이션

Research Category
Epigenetics & Nuclear Function

Apoptosis & Cancer

Research Sub Category
Cell Cycle, DNA Replication & Repair

This Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 Alexa Fluor 488 is validated for use in WB, FC for the detection of phospho-SMC1 (Ser957).

품질

Evaluated by Flow Cytometry with Hela Cells

표적 설명

150kDa Calculated

물리적 형태

Protein G Purified

Purified mouse monoclonal IgG1 conjugated to Alexa Flour 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

저장 및 안정성

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months from date of receipt. Protect from light.

분석 메모

Control
HeLa Cells

법적 정보

ALEXA FLUOR is a trademark of Life Technologies

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable