559276

Ryanodine

≥98% (HPLC), solid, Ca2+ release blocker, Calbiochem^®

• 동의어(들): Ryanodine, High Purity
• 실험식(Hill 표기법): C₂₅H₃₅NO₉
• CAS Number: 15662-33-6
• Molecular Weight: 493.55
• MDL number: MFCD00151119
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: Ryanodine, High Purity, Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum.
• 설명: Merck USA index - 14, 8307
• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white
• solubility: water: 1 mg/mL; methanol: 20 mg/mL
• 배송 상태: ambient
• 저장 온도: 10-30°C
• SMILES string: [nH]1c(ccc1)C(=O)O[C@H]2[C@@]3([C@]4([C@]65O[C@]([C@]4([C@@]2(O)C(C)C)C)(C[C@]3([C@]6(CC[C@@H]([C@H]5O)C)O)C)O)O)O
• InChI: 1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12-13,15,17,26-27,29-33H,8-9,11H2,1-5H3/t13-,15+,17+,18-,19-,20-,21-,22+,23+,24+,25+/m0/s1
• InChI key: JJSYXNQGLHBRRK-YSOSZROBSA-N

설명

일반 설명

Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle. Purified from Ryanodine Mixture.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Ca2+ transport and action in muscle

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Harmful (C)

재구성

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

기타 정보

Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci.14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res.56, 133.
Sukto, J.L., et al. 1985. Fed. Proc.44, 2984.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H302 + H312,H410
• 예방조치 성명서: P264 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable