추천 제품
설명
n-dodecylphosphocholine
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 1 g (850336P-1g)
pkg of 1 × 25 g (850336P-25g)
pkg of 1 × 5 g (850336P-5g)
제조업체/상표
Avanti Research™ - A Croda Brand
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCC
InChI
1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3
InChI key
QBHFVMDLPTZDOI-UHFFFAOYSA-N
일반 설명
Dodecylphosphocholine is a structural analog of lauroyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification.Dodecylphosphocholine has been shown to improve paracellular permeability of hydrophilic compounds by modulating the tight junctions. This may have implications on its use for oral or nasal drug delivery.
MAPCHO™-12 or n-dodecylphosphocholine is a detergent with short chain.
애플리케이션
MAPCHO™-12 is suitable for use as detergent for B. subtilis cytochrome b558 protein for nuclear magnetic resonance experiments. It is also suitable for use in the purification of cytoplasmic tail of gp41 (gp41CT) protein and micelle preparation.
생화학적/생리학적 작용
MAPCHO™-12 or n-dodecylphosphocholine in combination with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is used for membrane-mimetic bicelle system for orientation based studies in membrane proteins. It provides a zwitterionic surface in the membrane micelle structure.
포장
125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-5g)
20 mL Clear Glass Screw Cap Vial (850336P-1g)
250 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-25g)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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