862207
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
purified by recrystallization
동의어(들):
2-Phenyl-1-4-heteromethylene-5-oxazolone, 2-Phenyl-4-(ethoxymethylene)-2-oxazolinone, 2-Phenyl-4-(ethoxymethylene)oxazolone, 2-Phenyl-4-ethoxymethylene-5-oxazolone, 4-(Ethoxymethylene)-2-phenyl-5(4H)-oxazolone, 4-Ethoxymethylene-2-phenyl oxazolone, 4-Ethoxymethylene-2-phenyl-5-oxazolone, Oxazolone
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C12H11NO3
CAS Number:
Molecular Weight:
217.22
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
양식
solid
Quality Level
정제법
recrystallization
mp
94-96 °C (dec.) (lit.)
작용기
ester
ether
phenyl
저장 온도
2-8°C
SMILES string
CCO\C=C1/N=C(OC1=O)c2ccccc2
InChI
1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8-
InChI key
SJHPCNCNNSSLPL-NTMALXAHSA-N
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일반 설명
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one is a heterocyclic compound that belongs to the oxazolone family and serves as an important intermediate in the synthesis of amino acids, peptides, and heterocyclic precursors.
애플리케이션
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one can be used as a reactant to synthesize:
- Pyrimidinone derivatives with N-carboxymethylbenzamidine.
- Multi-functionalized 1-azabicycles with acyclic enaminones via formal aza-[3+3] cycloaddition.
이미 열람한 고객
Yongyan Shi et al.
Cell death & disease, 11(6), 461-461 (2020-06-17)
Crohn's disease (CD) and ulcerative colitis (UC) actually had different pathological mechanisms, as the former was mainly induced by Th1 and Th17 response and the latter by Th2 response. Our previous study found that oxazolone-induced Th2-mediated colitis could not be
Kenjyo Miyauchi et al.
Nature chemical biology, 9(2), 105-111 (2012-12-18)
N(6)-threonylcarbamoyladenosine (t(6)A) is a universally conserved, essential modified nucleoside found in transfer RNAs (tRNAs) responsible for ANN codons in all three domains of life. t(6)A has a crucial role in maintaining decoding accuracy during protein synthesis. The presence of t(6)A
IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function.
Amanda Waddell et al.
Inflammatory bowel diseases, 21(12), 2737-2746 (2015-08-28)
IL-33, a member of the IL-1 cytokine family that signals through ST2, is upregulated in ulcerative colitis (UC); however, the role of IL-33 in colitis remains unclear. IL-33 augments type 2 immune responses, which have been implicated in UC pathogenesis.
Boyi Liu et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(9), 3549-3563 (2013-06-01)
Allergic contact dermatitis is a common skin disease associated with inflammation and persistent pruritus. Transient receptor potential (TRP) ion channels in skin-innervating sensory neurons mediate acute inflammatory and pruritic responses following exogenous stimulation and may contribute to allergic responses. Genetic
Sylvère Durand et al.
The journal of physical chemistry. A, 117(12), 2508-2516 (2013-02-27)
The structure of peptide fragments was studied using "action" IR spectroscopy. We report on room temperature IR spectra of b4 fragments of protonated GGGGG, AAAAA, and YGGFL in the X-H (X = C, N, O) stretching region. Experiments were performed
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