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Merck
모든 사진(1)

주요 문서

6906-50A

Sigma-Aldrich

Human Peripheral Blood Monocytes: HPBM

동의어(들):

HPBM, HPBM cells

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About This Item

UNSPSC 코드:
41106514
NACRES:
NA.81

생물학적 소스

human peripheral blood

양식

liquid

포장

pkg of 5,000,000 cells

제조업체/상표

Cell Applications, Inc

성장 모드

Suspension

기술

cell culture | mammalian: suitable

배송 상태

dry ice

저장 온도

−196°C

일반 설명

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Human Peripheral Blood Monocytes (HPBM) provide a useful in vitro tool for studying various aspects of pathology and biology. Our CD14+ Monocytes are isolated and purified from human peripheral blood of healthy donors and cryopreserved immediately after isolation.

HPBM are the precursors of tissue macrophages and dentritic cells and are central to immunological responses, including cell-mediated cytotoxicity and production of inflammatory mediators. The CD14 monocyte subset expresses a component of the lipopolysaccharide (LPS) receptor complex, are large with diameter of ~18 um, represent ~80%–90% of circulating monocytes, and express higher levels of CD62L (L-selectin) and CD11b (also referred to as Mac-1 or CR3) and lower levels of MHC class II than do CD16+ monocytes.

세포주 기원

Blood

애플리케이션

Immune system dysfunction. Immunological responses, cell-mediated cytotoxicity, production of inflammatory mediators, hematopoiesis, myeloid differentiation, lipopolysaccharide (LPS), receptor complexes, CD62L (L-selectin), CD11b (Mac-1 or CR3), MHC class II.

포장

Immediately after isolation, 5,000,000 cells in DMEM containing 45% FBS & 10% DMSO.

성분

DMEM containing 45% FBS & 10% DMSO

품질

Each lot was tested for proper morphology, CD14 positive selection, Negative for HIV, Hepatitis B, Hepatitis C

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Natalie S Holman et al.
Toxicological sciences : an official journal of the Society of Toxicology, 170(2), 499-508 (2019-05-17)
Most idiosyncratic drug-induced liver injury appears to result from an adaptive immune attack on the liver. Recent evidence suggests that the T-cell response may be facilitated by the loss of immune tolerance. In this study, we explored the hypothesis that

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