516031

Methyl (S)-(−)-N-Z-aziridine-2-carboxylate

96%

• 동의어(들): (2S)-1,2-Aziridinedicarboxylic acid 2-methyl 1-(phenylmethyl) ester, (S)-N-Cbz-aziridine-2-carboxylic acid methyl ester, 1-Benzyl 2-methyl (S)-(−)-1,2-aziridinedicarboxylate, Methyl (S)-N-Cbz-aziridine-2-carboxylate
• 실험식(Hill 표기법): C₁₂H₁₃NO₄
• CAS Number: 104597-98-0
• Molecular Weight: 235.24
• MDL number: MFCD06799020
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24873860
• NACRES: NA.22

속성

• 분석: 96%
• 광학 활성: [α]20/D −25°, c = 1 in toluene
• refractive index: n20/D 1.519 (lit.)
• bp: 160-165 °C/2 mmHg (lit.)
• density: 1.19 g/mL at 25 °C (lit.)
• 작용기: ester; phenyl
• SMILES string: COC(=O)C1CN1C(=O)OCc2ccccc2
• InChI: 1S/C12H13NO4/c1-16-11(14)10-7-13(10)12(15)17-8-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3/t10-,13?/m0/s1
• InChI key: GTZJUBQWCWZING-NKUHCKNESA-N

설명

일반 설명

Methyl (S)-(−)-N-Z-aziridine-2-carboxylate is commonly used as an electrophilic aziridination reagent in organic synthesis. It is a chiral bicyclic lactam reagent that can be used for the synthesis of chiral aziridines from alkenes. The reagent is particularly useful in the synthesis of chiral building blocks.

애플리케이션

Methyl (S)-(−)-N-Z-aziridine-2-carboxylate can be used as a reactant in the total synthesis of α-C-mannosyltryptophan (C-Man-Trp), a naturally occurring C-glycosylamino acid. It is also used in the preparation of optically active aziridine derivatives.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves