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Merck
모든 사진(2)

주요 문서

369799

Sigma-Aldrich

(tert-Butoxycarbonylmethylene)triphenylphosphorane

98%

동의어(들):

tert-Butyl(triphenylphosphoranylidene)acetate

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About This Item

Linear Formula:
(C6H5)3P=CHCO2C(CH3)3
CAS Number:
Molecular Weight:
376.43
EC Number:
MDL number:
UNSPSC 코드:
12352108
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

98%

양식

solid

반응 적합성

reaction type: C-C Bond Formation

mp

152-155 °C (lit.)

작용기

ester
phosphine

저장 온도

2-8°C

SMILES string

CC(C)(C)OC(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C24H25O2P/c1-24(2,3)26-23(25)19-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-19H,1-3H3

InChI key

ZWZUFQPXYVYAFO-UHFFFAOYSA-N

애플리케이션

Wittig reagent used in the synthesis of aldose reductase inhibitors, a podophyllotoxin derivative, and tautomycin.
Versatile Wittig reagent used in medicinal chemistry.

픽토그램

Skull and crossbonesHealth hazardEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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문서 라이브러리 방문

이미 열람한 고객

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The Journal of Organic Chemistry, 57, 2922-2922 (1992)
George Kokotos et al.
Journal of medicinal chemistry, 47(14), 3615-3628 (2004-06-25)
The Group IVA cytosolic phospholipase A(2) (GIVA PLA(2)) is a particularly attractive target for drug development because it is the rate-limiting provider of proinflammatory mediators. We previously reported the discovery of novel 2-oxoamides that inhibit GIVA PLA(2) [Kokotos, G.; et
Tetrahedron Letters, 35, 4809-4809 (1994)
B L Mylari et al.
Journal of medicinal chemistry, 35(12), 2155-2162 (1992-06-12)
Benzothiazole side chains featured in zopolrestat (1a) and its congeners were incorporated into oxophthalazineacetic acid replacements, including indazole, pyridazinone, and pyridopyridazinone with a pendant acetic acid moiety. Potent aldose reductase inhibition activity among resulting compounds is as widespread as it
Fritz Sieber et al.
Phosphorus, sulfur, and silicon and the related elements, 180(3-4), 647-657 (2006-02-24)
Elemental selenium generated by the photobleaching of selenomerocyanine dyes forms conjugates with serum albumin and serum lipoproteins that are toxic to leukemia and selected solid tumor cells but well tolerated by normal CD34-positive hematopoietic stem and progenitor cells. Serum albumin

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