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Merck
모든 사진(2)

주요 문서

261394

Sigma-Aldrich

1,1-Dimethylurea

99%

동의어(들):

N,N-Dimethylurea

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About This Item

Linear Formula:
(CH3)2NCONH2
CAS Number:
Molecular Weight:
88.11
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

99%

양식

solid

mp

178-183 °C (lit.)

solubility

water: soluble 5%, clear, colorless

작용기

amine

SMILES string

CN(C)C(N)=O

InChI

1S/C3H8N2O/c1-5(2)3(4)6/h1-2H3,(H2,4,6)

InChI key

YBBLOADPFWKNGS-UHFFFAOYSA-N

유전자 정보

human ... EPHX2(2053)
mouse ... Ephx2(13850)

일반 설명

Nonlinear optical properties of 1,1-dimethylurea (N,N′ dimethylurea), have been evaluated through second-harmonic generation.

애플리케이션

1,1-Dimethylurea (N,N-dimethylurea) has been used in the Dowex-50W ion exchange resin-promoted synthesis of N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

S Sandler et al.
Diabetologia, 23(4), 374-378 (1982-10-01)
The protective effect on streptozotocin-induced diabetes of dimethyl urea, a hydroxyl radical scavenger, has been evaluated in vivo and in vitro. Pretreatment with dimethyl urea before a single diabetogenic dose of streptozotocin partially protected NMRI mice from hyperglycaemia, whereas the
Nonlinear optical properties of N, N' dimethylurea.
Halbout JM, et al.
Applied Physics Letters, 37(10), 864-866 (2008)
G L Wilson et al.
Diabetologia, 27(6), 587-591 (1984-12-01)
In studies to evaluate possible inhibitors of the B-cell toxin, streptozotocin, the superoxide scavenger, superoxide dismutase, did not prevent or reduce the toxic effects of streptozotocin as determined by loss of insulin secretion from rat pancreatic B cells in monolayer
G P Meshram et al.
Mutation research, 279(4), 275-280 (1992-06-16)
Methyl isocyanate (MIC) in aqueous solution forms methylamine (MA) and N,N'-dimethylurea (DMU). MA in buffered system further converts into its salt form, methylamine hydrochloride (MAH). Therefore, MAH and DMU were evaluated for their mutagenic activity in the in vitro Ames
W J Caspary et al.
Mutation research, 174(4), 285-293 (1986-08-01)
Methylisocyanate (MIC) induced mutagenic responses in the absence of exogenous activation in the mouse lymphoma cell forward mutation assay at concentrations as low as 8-24 microM. MIC produced predominantly small mutant colonies, suggesting the possibility of clastogenic activity. The intermediate

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