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Merck
모든 사진(3)

주요 문서

158186

Sigma-Aldrich

Ethylenediamine-N,N′-diacetic acid

≥98%

동의어(들):

EDDA, N,N′-Ethylenediglycine

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About This Item

Linear Formula:
HOOCCH2NHCH2CH2NHCH2COOH
CAS Number:
Molecular Weight:
176.17
Beilstein:
1778355
EC Number:
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

≥98%

mp

224 °C (dec.) (lit.)

작용기

amine
carboxylic acid

SMILES string

OC(=O)CNCCNCC(O)=O

InChI

1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)

InChI key

IFQUWYZCAGRUJN-UHFFFAOYSA-N

애플리케이션

Ethylenediamine-N,N′-diacetic acid (EDDA) is a chelating agent that can be used to synthesize:
  • Binary and ternary copper(II) complexes with potent proteasome inhibitory properties.
  • Pd(EDDA) complexes which can coordinate with amino acids, peptides, or DNA units.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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Clara L Santos-Cuevas et al.
Nuclear medicine communications, 29(8), 741-747 (2008-08-30)
The gastrin-releasing peptide receptor (GRP-R) is expressed in several normal human tissues and is overexpressed in various human tumors including breast, prostate, small-cell lung cancer and pancreatic cancer. Recently, 99mTc-EDDA/HYNIC-[Lys]-bombesin (99mTc-HYNIC-BN) was reported as a radiopharmaceutical with high stability in
Olivier Dalmas et al.
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The transmembrane conformation of Thermotoga maritima CorA, a magnesium transport system, has been studied in its Mg(2+)-bound form by site-directed spin labeling and electron paramagnetic resonance spectroscopy. Probe mobility together with accessibility data were used to evaluate the overall dynamics
Alma D Miranda-Olvera et al.
Bioconjugate chemistry, 18(5), 1560-1567 (2007-08-02)
Two synthetic procedures for HYNIC oxytocin labeling were developed: one based on an orthogonal protection approach and the other with prelabeled (Boc)HYNIC-(Fmoc) amino acids. Both procedures were compared and applied to the preparation of several HYNIC-oxytocin derivatives where ligand position
Jelena M Vujić et al.
European journal of medicinal chemistry, 45(9), 3601-3606 (2010-06-24)
Four novel bidentate N,N'-ligand precursors, including O,O'-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), L1 x 2 HCl-L4 x 2 HCl, of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid dihydrochloride [(S,S)-H(4)eddl]Cl(2) and the corresponding palladium(II) complexes 1-4, were prepared and characterized by IR, (1)H
Levente K Meszaros et al.
Dalton transactions (Cambridge, England : 2003), 40(23), 6260-6267 (2011-02-26)
6-Hydrazinonicotinic acid (HYNIC, 1) is a well-established bifunctional technetium-binding ligand often used to synthesise bioconjugates for radiolabelling with Tc-99m. It is capable of efficient capture of technetium at extremely low concentrations, but the structure of the labelled complexes is heterogeneous

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