콘텐츠로 건너뛰기
Merck

EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

동의어:
4E-BP1, 4EBP1, BP-1, PHAS-I
:
UniProtKB ID:
Clone ID:
  • Human(1978) Summary: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
  • Mouse(13685) eukaryotic translation initiation factor 4E binding protein 1
  • Rat(116636) eukaryotic translation initiation factor 4E binding protein 1
  • Zebrafish(799566) eukaryotic translation initiation factor 4E binding protein 1
  • dog(475590) eukaryotic translation initiation factor 4E binding protein 1
  • cow(509613) eukaryotic translation initiation factor 4E binding protein 1
  • domestic cat(101088571) eukaryotic translation initiation factor 4E binding protein 1
  • chicken(426773) eukaryotic translation initiation factor 4E binding protein 1
  • naked mole-rat(101710614) eukaryotic translation initiation factor 4E binding protein 1
  • domestic guinea pig(100733182) eukaryotic translation initiation factor 4E binding protein 1
  • Goat(100861097) eukaryotic translation initiation factor 4E binding protein 1
  • sheep(101111426) eukaryotic translation initiation factor 4E binding protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-4E-BP1 (pThr70) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
Anti-EIF4EBP1 (Ab-45) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot

Proteins

제품 번호
설명
4EBP1, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human
4EBP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human
4EBP1 Active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human EIF4EBP1,
human
MISSION® esiRNA, targeting mouse Eif4ebp1,
mouse