Antibiotics
The use of antibiotics in cell cultures prevents contamination from pathogens that induce morphological or physiological changes in cell cultivation as well as contamination of cell lines. Antibiotics, such as penicillin, puromycin, and ampicillin, are molecules that specifically target and kill cells by inhibiting or regulating cell-wall synthesis, nucleic acid metabolism and protein synthesis, or disrupting membrane structure. test2304
We offer a wide variety of effective antibiotics, antibiotic extraction kits, and antibiotic ready-made solutions in varying concentrations for reliable results in your lab. Our antibacterial, antiviral, antifungal, and antineoplastic agents control and eradicate cell culture contamination to maintain aseptic conditions in your lab. Moreover, certain antibiotics also function as selection agents to establish transfected/genetically modified cells depending on your research needs.
Selecting the right antibiotics for your cell contamination prevention, genetic marker selection and cell biology studies is driven by application information, activity spectrum, and usage data. Browse antibiotics by mechanism of action or by spectrum of activity.
| Antibiotics by Mechanism of Action | Antibiotics by Spectrum of Activity | |
Keeping your focus on creating breakthroughs, explore our full portfolio of reliable antibiotics below.
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Related Resources
- Průvodce výběrem antibiotik pro buněčné kultury
Průvodce výběrem antibiotik pro buněčné kultury, včetně antibiotik pro buněčné kultury savců, rostlinné buněčné kultury a selekčních antibiotik pro buněčné kultury.
- Antibiotics in Plant Tissue Culture Protocol
Reference guide and preparation guide for antibiotic and antimycotic use in plant tissue culture.
- Antibiotic Optimization for Cell Transduction Using a Cytotoxicity Profile
Experimentally determine the appropriate antibiotic concentration for selecting stable cell lines. This titration protocol can determine the lowest concentration of puromycin needed to efficiently select transduced cells.
- Proč používat antibiotika v buněčných kulturách?
Vědět, kdy použít antibiotika, aby se zabránilo bakteriální nebo plísňové, mykoplasmatické nebo virové kontaminaci buněčné kultury, a najít vhodná antibiotika nebo jiné biologické látky.
- Inhibice biosyntézy buněčné stěny antibiotiky
β-laktamová antibakteriální léčiva inhibují enzymy transpeptidázy, čímž zabraňují sestavování peptidoglykanu u grampozitivních i gramnegativních bakterií.
- Inhibition of Protein Synthesis by Antibiotics
Protein synthesis is a complex, multi-step process involving many enzymes as well as conformational alignment. However, the majority of antibiotics that block bacterial protein synthesis interfere with the processes at the 30S subunit or 50S subunit of the 70S bacterial ribosome.
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