1012123

Adenosine

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 9-β-D-Ribofuranosyladenine, Adenine riboside, Adenine-9-β-D-ribofuranoside
• Formule empirique (notation de Hill) : C₁₀H₁₃N₅O₄
• Numéro CAS: 58-61-7
• Poids moléculaire : 267.24
• Beilstein: 93029
• Numéro MDL: MFCD00005752
• Code UNSPSC : 41116107
• ID de substance PubChem : 329748939
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Description: API family: adenosine
• Famille d'API: adenosine
• Forme: solid
• Fabricant/nom de marque: USP
• Pf: 234-236 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
• InChI: 1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
• Clé InChI: OIRDTQYFTABQOQ-KQYNXXCUSA-N
• Informations sur le gène: human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140)

Description

Description générale

Adenosine is a nucleoside formed by the attachment of adenine to a ribose sugar. The USP Adenosine standard provides a reference for the quality and purity of adenosine used in pharmaceutical formulations and research applications, ensuring consistency in its therapeutic and experimental use.

The USP biologics oligonucleotides category includes a variety of synthetic nucleic acid sequences that are essential in research, diagnostics, and therapeutic applications. These oligonucleotides play crucial roles in molecular biology, including gene expression regulation, antisense therapy, and RNA interference. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of oligonucleotide products throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Adenosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Adenosine Injection
• Heparin Sodium

Actions biochimiques/physiologiques

Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A₁ adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A₂ adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).

Endogenous neurotransmitter. Cardioprotective effects may relate to activation of A₁ adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A₂ adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

This product is part of USP Biologics Program.

Sales restrictions may apply.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable