SML3633

C23.28-TPP

≥98% (HPLC)

• Synonyme(s) : (6-(4-(2,5-Dimethylphenyl)-4-oxobutanoyloxy)hexyl)triphenylphosphonium bromide
• Formule empirique (notation de Hill) : C₃₆H₄₀O₃P·Br
• Numéro CAS: 2595181-54-5
• Poids moléculaire : 631.58
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: DMSO: 2 mg/mL, clear
• Température de stockage: 2-8°C

Description

Actions biochimiques/physiologiques

Bacteria-permeable prodrug inhibitor of IspH

C23.28-TPP is a bacteria-permeable prodrug inhibitor of IspH that is bactericidal to number of multidrug-resistant bacteria including Acinetobacter, Pseudomonas, Klebsiella, Enterobacter, Vibrio, Shigella, Salmonella, Yersinia, Mycobacterium and Bacillus. It stimulates rapid immune response through activation human Vγ9Vδ2 T cells in a humanized mouse model of bacterial infection. C23.28-TPP was able to clear infection by a clinically isolated multidrug-resistant strain of E. aerogenes (UCI 15) in BALBc mice. It is relatively non-toxic to mammalian cells.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable