SML3479

Hydroxy-α-sanshool

≥95% (HPLC)

• Synonyme(s) : (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide, 2E,6Z,8E,10E-Dodecatetraenoic acid N-(2-hydroxy-2-methylpropyl)amide
• Formule empirique (notation de Hill) : C₁₆H₂₅NO₂
• Numéro CAS: 83883-10-7
• Poids moléculaire : 263.38
• Numéro MDL: MFCD17779317
• Code UNSPSC : 51111800
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (HPLC)
• Forme: powder
• Conditions de stockage: protect from light; under inert gas
• Couleur: white to beige
• Solubilité: DMSO: 2 mg/mL, clear
• Température de stockage: -10 to -25°C
• Chaîne SMILES: N(CC(O)(C)C)C(=O)\C=C\CC\C=C/C=C/C=C/C
• InChI: 1S/C16H25NO2/c1-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(2,3)19/h4-9,12-13,19H,10-11,14H2,1-3H3,(H,17,18)/b5-4+,7-6+,9-8-,13-12+
• Clé InChI: LHFKHAVGGJJQFF-UEOYEZOQSA-N

Description

Actions biochimiques/physiologiques

Hydroxy-α-sanshool is an active ingredient in Szechuan peppers (also present in other Zanthoxylum plants) that produces a tingling paresthesia or numbing effects. Hydroxy-α-sanshool is a potent agonist of TRPV1/TRPA1 as well as antagonist/blocker of KCNK3/KCNK9/KCNK18 channels. It induces colonic motor activity in rat proximal colon.

Potent agonist of TRPV1/TRPA1 as well as antagonist/blocker of KCNK3/KCNK9/KCNK18 channels

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable