SML1434

UNC2170 trifluoroacetate

≥98% (HPLC)

• Synonyme(s) : 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide trifluoroacetate salt
• Formule empirique (notation de Hill) : C₁₄H₂₁BrN₂O · C₂HF₃O₂
• Numéro CAS: 1648707-58-7
• Poids moléculaire : 427.26
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825874
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: oil
• Couleur: colorless to yellow
• Température de stockage: 2-8°C
• Chaîne SMILES: BrC1=CC=CC(C(NCCCNC(C)(C)C)=O)=C1.FC(F)(C(O)=O)F
• InChI: 1S/C14H21BrN2O.C2HF3O2/c1-14(2,3)17-9-5-8-16-13(18)11-6-4-7-12(15)10-11;3-2(4,5)1(6)7/h4,6-7,10,17H,5,8-9H2,1-3H3,(H,16,18);(H,6,7)
• Clé InChI: DPAGQICQYYQSQP-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

UNC2170 is an inhibitor of DNA damage response protein 53BP1, which recognizes dimthyl lysine residues on lysine 20 on histone H4 that is involved in double-strand DNA breaks. 17-fold selectivity for 53BP1 as compared to other methyl-lysine (Kme) binding proteins tested.

UNC2170 is an inhibitor of DNA damage response protein 53BP1.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable