SBR00098

Tazemetostat

≥98% (HPLC), powder

• Synonyme(s) : EPZ6438
• Formule empirique (notation de Hill) : C₃₄H₄₄N₄O₄
• Numéro CAS: 1403254-99-8
• Poids moléculaire : 572.74
• Code UNSPSC : 51101500

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to off-white
• Mode d’action: protein synthesis | inhibits
• Température de stockage: 2-30°C
• Chaîne SMILES: CCN(C1CCOCC1)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C4=CC=C(C=C4)CN5CCOCC5
• InChI: InChI=1S/C34H44N4O4/c1-5-38(29-10-14-41-15-11-29)32-20-28(27-8-6-26(7-9-27)22-37-12-16-42-17-13-37)19-30(25(32)4)33(39)35-21-31-23(2)18-24(3)36-34(31)40/h6-9,18-20,29H,5,10-17,21-22H2,1-4H3,(H,35,39)(H,36,40)
• Clé InChI: NSQSAUGJQHDYNO-UHFFFAOYSA-N

Description

Description générale

Tazemetostat is a small molecule inhibitor of the EZH2 protein, which is a histone-lysine N-methyltransferase enzyme that plays a key role in epigenetic regulation of gene expression.

Actions biochimiques/physiologiques

Tazemetostat inhibits the EZH2 protein. EZH2 is a histone-lysine N-methyltransferase enzyme that plays a key role in epigenetic regulation of gene expression in cells. As an epigenetic modifier, EZH2 protein controls the transcriptional repression of various genes involved in cell cycle regulation, DNA repair, and other cellular processes.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable