SBR00086

Remdesivir

≥98% (HPLC), powder

• Formule empirique (notation de Hill) : C₂₇H₃₅N₆O₈P
• Numéro CAS: 1809249-37-3
• Poids moléculaire : 602.58
• Code UNSPSC : 51101500

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to off-white
• Spectre d'activité de l'antibiotique: viruses
• Mode d’action: DNA synthesis | inhibits
• Conditions d'expédition: ambient
• Chaîne SMILES: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
• InChI: 1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1
• Clé InChI: RWWYLEGWBNMMLJ-YSOARWBDSA-N

Description

Description générale

Remdesiviris is an antibioitic which belongs to the class of compounds known as nucleotide analogues. Remdesivir has broad spectrum antiviral activity against RNA viruses.

Actions biochimiques/physiologiques

Remdesivir inhibits viral RNA synthesis, which is essential for the replication of RNA viruses. Remdesivir is a nucleotide analogue, which means that it is designed to mimic the structure of natural nucleotides, the building blocks of RNA and DNA. When remdesivir is incorporated into the viral RNA by the viral RNA polymerase, it terminates RNA synthesis prematurely, preventing further replication of the viral RNA. This leads to the inhibition of viral replication and the reduction of viral load, which can help to reduce the severity of viral infections. Remdesivir has been shown to be active against a broad range of RNA viruses, including coronaviruses, filoviruses, and paramyxoviruses, among others.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H373
• Conseils de prudence: P260 - P314 - P501
• Classification des risques: STOT RE 2 Oral
• Organes cibles: Kidney
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3