SBR00085

Orbifloxacin

≥95% (H-NMR), powder

• Formule empirique (notation de Hill) : C₁₉H₂₀F₃N₃O₃
• Numéro CAS: 113617-63-3
• Poids moléculaire : 395.38
• Code UNSPSC : 51101500

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (H-NMR)
• Forme: powder
• Couleur: off-white to yellow
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: DNA synthesis | inhibits
• Température de stockage: 2-30°C
• Chaîne SMILES: C[C@@H]1CN(C[C@@H](N1)C)C2=C(C3=C(C(=C2F)F)C(=O)C(=CN3C4CC4)C(=O)O)F
• InChI: InChI=1S/C19H20F3N3O3/c1-8-5-24(6-9(2)23-8)17-14(21)13(20)12-16(15(17)22)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6H2,1-2H3,(H,27,28)/t8-,9+
• Clé InChI: QIPQASLPWJVQMH-DTORHVGOSA-N

Description

Description générale

Orbifloxacin is a fluoroquinolone antibiotic which inhibits bacterial growth by inhibiting DNA gyrase and topoisomerase IV.

Application

Orbifloxacin has very limited non-medical applications, as it is primarily known and used as a veterinary antibiotic for the treatment of bacterial infections in animals. However, it can be used as a reference standard in analytical chemistry for the development and validation of methods for the detection and quantification of fluoroquinolone antibiotics, such as Orbifloxacin, in various samples, such as food, environmental, and biological samples. Orbifloxacin has been used as a standard for the analysis of fluoroquinolone antibiotics in food products, such as meat, milk, and eggs, as well as in environmental samples, such as water and soil. Moreover, its potential use in animals, particularly livestock and poultry, highlights the importance of prudent use and management of the antibiotic to prevent the development and spread of antibiotic-resistant bacteria.

Actions biochimiques/physiologiques

Orbifloxacin inhibits bacterial DNA synthesis through interference with the activity of DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication, transcription, and repair of bacterial DNA. Orbifloxacin is active against Gram-negative and Gram-positive bacteria, including many strains of Escherichia coli, Pasteurella, Streptococcus, and Staphylococcus species.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable