SBR00081

Favipiravir

≥97% (HPLC), powder

• Synonyme(s) : Favilavir, T-705
• Formule empirique (notation de Hill) : C₅H₄FN₃O₂
• Numéro CAS: 259793-96-9
• Poids moléculaire : 157.10
• Code UNSPSC : 51101500

Propriétés

• Niveau de qualité: 100
• Essai: ≥97% (HPLC)
• Forme: powder
• Couleur: white to yellow
• Spectre d'activité de l'antibiotique: viruses
• Mode d’action: enzyme | inhibits
• Température de stockage: −20°C
• Chaîne SMILES: C1=C(N=C(C(=O)N1)C(=O)N)F
• InChI: InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
• Clé InChI: ZCGNOVWYSGBHAU-UHFFFAOYSA-N

Description

Description générale

Favipiravir is a pyrazinecarboxamide derivative which is an RNA polymerase inhibitors. Favipiravir is converted to the ribofuranosyltriphosphate derivative by host enzymes and selectively inhibits the influenza viral RNA-dependent RNA polymerase. Favipiravir has broad-spectrum activity against RNA viruses, including influenza viruses, arena viruses, bunyaviruses, and flaviviruses.

Actions biochimiques/physiologiques

Favipiravir inhibits the RNA-dependent RNA polymerase enzyme, which is essential for the replication of RNA viruses such as influenza and SARS-CoV-2 (the virus that causes COVID-19). Inhibition of RNA-dependent RNA polymerase activity leads to the disruption of viral RNA replication and ultimately, the reduction of viral load.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H341,H361d
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Muta. 2 - Repr. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable