SBR00075

Avibactam Sodium Salt

≥97% (HPLC), powder

• Synonyme(s) : NXL-104
• Formule empirique (notation de Hill) : C₇H₁₁N₃NaO₆S
• Numéro CAS: 1192491-61-4
• Poids moléculaire : 288.23
• Code UNSPSC : 51101500

Propriétés

• Niveau de qualité: 100
• Essai: ≥97% (HPLC)
• Forme: powder
• Conditions de stockage: under inert gas (Nitrogen)
• Couleur: white
• Spectre d'activité de l'antibiotique: Gram-negative bacteria
• Mode d’action: enzyme | inhibits
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+]
• InChI: InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
• Clé InChI: RTCIKUMODPANKX-JBUOLDKXSA-M

Description

Description générale

Avibactam sodium is a β-lactamase inhibitor and β-Lactamases are responsible for resistance to penicillins, monobactams, carbapenems, and extended-spectrum cephalosporins. It is a synthetic molecule with activity against gram-negative bacteria.

Application

Avibactam and related compounds have been studied for their ability to inhibit a variety of beta-lactamases, which are enzymes that inactivate beta-lactam antibiotics such as penicillin. The development of new beta-lactamase inhibitors like Avibactam is important for combating antibiotic resistance.

Actions biochimiques/physiologiques

Avibactam is a β-lactamase inhibitor which inhibits the activity of β-lactamases by binding to the active site of β-lactamases and blocks the access of the substrate to the enzyme. Avibactam is effective against bacteria resistant to ceftazidime like Escherichia coli.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable